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Common substances such as pollen, dust particles, animal dander (pieces of dry skin, hair and fur), and mould spores can prompt a severe reaction in people who are allergic to them.

These substances are collectively referred to as "allergens".

Mast cells do not usually circulate in the blood stream but settle in the connective tissue in the dermis.

About 20% or more of older American adults use some form of sleep aid, including prescription or over-the-counter drugs or alcohol. Over-the-counter or nonprescription medications make use of the drowsiness caused by some common medications.

Topics are richly illustrated with more than 40,000 clinical photos, videos, diagrams, and radiographic images.

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†A minimum of 72 hours is required as a ground trial at initiation of therapy to ensure adequate symptom control and to exclude idiosyncratic reaction.

Prescription drugs used specifically for improving sleeping are called sedative hypnotics.